| A longitudinal study of nonvitamin, nonmineral supplement use: prevalence, associations, and survival in an aging population. | |
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MedLine Citation:
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PMID: 17890106 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: We sought to describe population and survival characteristics in nonvitamin, nonmineral (NVNM) supplement users in a population-based cohort study. METHODS: People from 43 to 86 years of age living in Beaver Dam, Wisconsin, participated in a baseline examination from 1988 to 1990 (n = 4,926) and three follow-up examinations at 5-year intervals (n = 3,722, 2,962, 2,375 at each successive examination). Medication and supplement use, medical and lifestyle factors were collected during the examination and survival was monitored through 2002. RESULTS: NVNM supplement use increased from 5% at baseline, to 6% at the second, to 21% at the third to 30% at the fourth examination. In general, younger age, vitamin or mineral use, and taking more medications was directly related to NVNM supplement use, while current smoking and history of other systemic diseases (e.g., cardiovascular disease, cancer) was inversely related to NVNM supplement use. After adjusting for age, sex, and other medical and lifestyle factors, users of NVNM supplements had lower mortality (hazard ratio, 0.74; 95% confidence interval, 0.57-0.95, p = 0.02) than nonusers. CONCLUSIONS: NVNM supplement users had a healthier lifestyle and fewer co-morbid medical conditions and were more likely to survive after adjusting for these factors than non-users. |
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Authors:
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Michael D Knudtson; Ronald Klein; Kristine E Lee; Jennifer O Reinke; Lorraine G Danforth; Angela M Wealti; Emily Moore; Barbara E K Klein |
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Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural Date: 2007-09-24 |
Journal Detail:
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Title: Annals of epidemiology Volume: 17 ISSN: 1047-2797 ISO Abbreviation: Ann Epidemiol Publication Date: 2007 Dec |
Date Detail:
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Created Date: 2007-11-20 Completed Date: 2008-04-16 Revised Date: 2010-08-30 |
Medline Journal Info:
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Nlm Unique ID: 9100013 Medline TA: Ann Epidemiol Country: United States |
Other Details:
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Languages: eng Pagination: 933-9 Citation Subset: IM |
Affiliation:
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Department of Ophthalmology and Visual Sciences, University of Wisconsin, School of Medicine and Public Health, Madison, WI 53726-2336, USA. knudtson@epi.ophth.wisc.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Age Factors Aged Aged, 80 and over Body Mass Index Cohort Studies Diet Dietary Supplements / utilization* Female Health Status Humans Life Style Longitudinal Studies Male Middle Aged Minerals / administration & dosage Prevalence Social Class Survival Analysis Vitamins / administration & dosage |
| Grant Support | |
ID/Acronym/Agency:
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EY06594/EY/NEI NIH HHS; U10 EY006594-20/EY/NEI NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Minerals; 0/Vitamins |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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