Document Detail


A longitudinal study of cell-mediated immunity in human pregnancy.
MedLine Citation:
PMID:  7277339     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Studies of cell-mediated immunity, comprising delayed hypersensitivity skin testing with four antigens, PHA and antigen-induced lymphocyte transformation and detection of the lymphokine, monocyte chemotactic factor, were undertaken in 14 women during pregnancy and in the post-natal period. Skin test reaction sizes to SKSD, PPD, Candida albicans extract and tetanus toxoid were not significantly different during pregnancy. In vitro lymphocyte transformation induced by PHA, SKSD and Candida albicans was enhanced during pregnancy. Monocyte chemotactic factor production was not significantly different during pregnancy. These in vitro tests were performed in the absence of autologous sera. These studies indicate that cell-mediated immune responses are normal during human pregnancy.
Authors:
C S Hawes; A S Kemp; W R Jones; J A Need
Related Documents :
17561269 - Postpartum-activation of multiple sclerosis is associated with down-regulation of toler...
20367629 - The immune system in pregnancy: a unique complexity.
904809 - Effects of pregnancy on the maternal lymphoid system in mice.
7045229 - The alloantibody response in the allogeneically pregnant rat. iii. the location of the ...
3584989 - Allogeneic matings and immunization have different effects on nulliparous and multiparo...
6097129 - Rh immune globulin after genetic amniocentesis: impact on pregnancy outcome.
2631539 - Human chorionic gonadotropin in cord blood and peripheral maternal blood in singleton a...
23168749 - Maternal and neonatal outcomes of dose-dense chemotherapy for breast cancer in pregnancy.
19963919 - Spatial analysis of uterine emg signals: evidence of increased in synchronization with ...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of reproductive immunology     Volume:  3     ISSN:  0165-0378     ISO Abbreviation:  J. Reprod. Immunol.     Publication Date:  1981 Jul 
Date Detail:
Created Date:  1981-11-22     Completed Date:  1981-11-22     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8001906     Medline TA:  J Reprod Immunol     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  165-73     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Female
Humans
Hypersensitivity, Delayed / diagnosis
Immunity, Cellular*
Longitudinal Studies
Lymphocyte Activation
Lymphokines / biosynthesis
Pregnancy*
Skin Tests
Chemical
Reg. No./Substance:
0/Lymphokines

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Immunological identification of lactoferrin as a shared antigen on radioiodinated human sperm surfac...
Next Document:  Effects of maternal anti H-Y antibodies on fetal gonadal development.