Document Detail

The long-term outcome of 946 consecutive couples visiting a fertility clinic in 2001-2003.
MedLine Citation:
PMID:  21550038     Owner:  NLM     Status:  Publisher    
OBJECTIVE: To describe the outcome of fertility work-up, treatment, and dropout in a cohort of subfertile couples in a well-defined area in Western Europe. DESIGN: Prospective cohort study. SETTING: Maastricht University Medical Center. PATIENT(S): Subfertile couples referred by their general physician between 2001 and 2003. INTERVENTION(S): Demographic data, findings of the fertility investigation, and outcome of treatment were entered prospectively into a database. Follow-up was performed until November 2008. MAIN OUTCOME MEASURE(S): Diagnosis, treatment, dropout rate, pregnancy rate, and live-birth rate. RESULT(S): During the study period, 946 couples were referred, of whom 17% dropped out. Follow-up was complete in 94% of couples. Spontaneous pregnancies occurred in 28% of all couples, and there were 32% treatment-dependent pregnancies. IVF (51% live births in couples treated) and no treatment/expectant management (50%) were the most effective treatments. CONCLUSION(S): After 5-8 years, 51% of couples referred for subfertility had at least one live birth.
Janneke Donckers; Johannes L H Evers; Jolande A Land
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-5-6
Journal Detail:
Title:  Fertility and sterility     Volume:  -     ISSN:  1556-5653     ISO Abbreviation:  -     Publication Date:  2011 May 
Date Detail:
Created Date:  2011-5-9     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0372772     Medline TA:  Fertil Steril     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2011 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.
Maastricht University Medical Centre, Department of Obstetrics and Gynaecology, and GROW, School for Oncology and Developmental Biology, Maastricht, the Netherlands; University Nijmegen Medical Centre, Department of Obstetrics and Gynaecology, Nijmegen, the Netherlands.
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