Document Detail


The long-term outcome of 946 consecutive couples visiting a fertility clinic in 2001-2003.
MedLine Citation:
PMID:  21550038     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
OBJECTIVE: To describe the outcome of fertility work-up, treatment, and dropout in a cohort of subfertile couples in a well-defined area in Western Europe. DESIGN: Prospective cohort study. SETTING: Maastricht University Medical Center. PATIENT(S): Subfertile couples referred by their general physician between 2001 and 2003. INTERVENTION(S): Demographic data, findings of the fertility investigation, and outcome of treatment were entered prospectively into a database. Follow-up was performed until November 2008. MAIN OUTCOME MEASURE(S): Diagnosis, treatment, dropout rate, pregnancy rate, and live-birth rate. RESULT(S): During the study period, 946 couples were referred, of whom 17% dropped out. Follow-up was complete in 94% of couples. Spontaneous pregnancies occurred in 28% of all couples, and there were 32% treatment-dependent pregnancies. IVF (51% live births in couples treated) and no treatment/expectant management (50%) were the most effective treatments. CONCLUSION(S): After 5-8 years, 51% of couples referred for subfertility had at least one live birth.
Authors:
Janneke Donckers; Johannes L H Evers; Jolande A Land
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-5-6
Journal Detail:
Title:  Fertility and sterility     Volume:  -     ISSN:  1556-5653     ISO Abbreviation:  -     Publication Date:  2011 May 
Date Detail:
Created Date:  2011-5-9     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0372772     Medline TA:  Fertil Steril     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2011 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.
Affiliation:
Maastricht University Medical Centre, Department of Obstetrics and Gynaecology, and GROW, School for Oncology and Developmental Biology, Maastricht, the Netherlands; University Nijmegen Medical Centre, Department of Obstetrics and Gynaecology, Nijmegen, the Netherlands.
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