| A long-term follow-up study in essential cryoglobulinemia. | |
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MedLine Citation:
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PMID: 105549 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In a case series of 56 patients with essential cryoglobulinemia, 35 were followed-up for 4-13 years (mean 7 years). A membranous proliferative glomerulonephritis, which in about half the cases showed a progression to renal insufficiency, was the commonest complication, observed in more than one third of the patients. In 2 patients hepatic cirrhosis became manifest after a completely asymptomatic period and in 2 others a lymphoproliferative disease appeared 2 and 8 years after the onset of purpura. In 51% of patients the intial clinical pattern did not change. In searching for a correlation between the development of nephropathy and cryoglobulin characteristics, none was demonstrated studying the cryoglobulin level, the presence of autoantibody and the complement components. |
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Authors:
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F Invernizzi; P Pioltelli; R Cattaneo; V Gavazzeni; P Borzini; G Monti; C Zanussi |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Acta haematologica Volume: 61 ISSN: 0001-5792 ISO Abbreviation: Acta Haematol. Publication Date: 1979 |
Date Detail:
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Created Date: 1979-04-25 Completed Date: 1979-04-25 Revised Date: 2005-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0141053 Medline TA: Acta Haematol Country: SWITZERLAND |
Other Details:
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Languages: eng Pagination: 93-9 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Antibodies / analysis Autoantibodies / analysis Complement System Proteins / analysis Cryoglobulins* / analysis DNA / immunology Female Follow-Up Studies Glomerulonephritis / etiology Humans Kidney Failure, Chronic / etiology Liver Cirrhosis / etiology Lymphoproliferative Disorders / etiology Male Middle Aged Paraproteinemias / blood, complications*, immunology Waldenstrom Macroglobulinemia / etiology |
| Chemical | |
Reg. No./Substance:
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0/Antibodies; 0/Autoantibodies; 0/Cryoglobulins; 9007-36-7/Complement System Proteins; 9007-49-2/DNA |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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