Document Detail

The long-term follow-up of the Hancock Modified Orifice porcine bioprosthetic valve.
MedLine Citation:
PMID:  1810546     Owner:  NLM     Status:  MEDLINE    
The Hancock Modified Orifice valve is a specially fabricated, trileaflet porcine valve, which has been in clinical use at the Brigham and Women's Hospital since 1976. Three hundred seventy-nine aortic valve replacements with this device were implanted from 1976 to 1985; 305 were isolated aortic valve replacements and 74 were in association with a mitral valve bioprosthesis. The 305 patients undergoing isolated aortic valve replacement, a Food and Drug Administration patient group, are the subject of this article. The mean valve size was 22.5 mm, with 115 21-mm valves used. The mean functional preoperative class was 3.2; 99 of 305 patients (32.5%) underwent concomitant coronary artery bypass grafting. There were six operative deaths (2%). Patients were followed from 6-14 years (mean 7.4 years), and analysis was completed in early 1991. The 10-year actuarial calculation of survival freedom from reoperation, thromboembolism, structural valve degeneration, perivalvular leak, infectious valve degeneration, and total morbidity and mortality are presented.
L H Cohn; G S Couper; S F Aranki; N M Kinchla; J J Collins
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of cardiac surgery     Volume:  6     ISSN:  0886-0440     ISO Abbreviation:  J Card Surg     Publication Date:  1991 Dec 
Date Detail:
Created Date:  1992-06-03     Completed Date:  1992-06-03     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8908809     Medline TA:  J Card Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  557-61     Citation Subset:  IM    
Division of Cardiac Surgery, Brigham and Women's Hospital, Boston, Massachusetts 02115.
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MeSH Terms
Actuarial Analysis
Aortic Valve
Follow-Up Studies
Heart Valve Prosthesis / adverse effects,  mortality*
Middle Aged
Mitral Valve
Survival Rate
Time Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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