Document Detail


A long-range repeat cluster in chromosome 1 of the house mouse, Mus musculus, and its relation to a germline homogeneously staining region.
MedLine Citation:
PMID:  1370812     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The laboratory mouse C57BL genome contains about 50 copies of a long-range repeat DNA family clustered in the C-D region of chromosome 1. The repeat length is more than 50 kb and includes sequences homologous to at least two mRNAs. There are small differences in the copies of this repeat family such as restriction site mutations and gross differences like rearrangements and insertions of LINE1 elements. A germline homogeneously staining region occurring as a chromosome 1 polymorphism in many feral populations of the house mouse is an amplified version of this long-range repeat cluster.
Authors:
L Purmann; C Plass; M Grüneberg; H Winking; W Traut
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Genomics     Volume:  12     ISSN:  0888-7543     ISO Abbreviation:  Genomics     Publication Date:  1992 Jan 
Date Detail:
Created Date:  1992-03-05     Completed Date:  1992-03-05     Revised Date:  2008-08-23    
Medline Journal Info:
Nlm Unique ID:  8800135     Medline TA:  Genomics     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  80-8     Citation Subset:  IM    
Affiliation:
Institute für Biologie, Medizinische Universität, Lübeck, Federal Republic of Germany.
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MeSH Terms
Descriptor/Qualifier:
Animals
Blotting, Southern
Cloning, Molecular
DNA Probes
Deoxyribonucleases, Type II Site-Specific / metabolism
Electrophoresis, Gel, Pulsed-Field
Gene Amplification
Genome
Germ Cells
Mice
Mice, Inbred C57BL
Muridae
Polymorphism, Restriction Fragment Length
Repetitive Sequences, Nucleic Acid*
Restriction Mapping
Sequence Homology, Nucleic Acid
Staining and Labeling
Chemical
Reg. No./Substance:
0/DNA Probes; EC 3.1.21.-/endodeoxyribonuclease SfiI; EC 3.1.21.4/Deoxyribonucleases, Type II Site-Specific; EC 3.1.21.4/GCGGCCGC-specific type II deoxyribonucleases

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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