Document Detail

A long-awaited discovery: hypoxia prevents mouse cells from undergoing spontaneous p53-dependent transformation.
MedLine Citation:
PMID:  22909278     Owner:  NLM     Status:  Publisher    
A recent publication by Phinney and his associates ( 1 ) has presented a discovery for which the field of cell biology has been waiting for more than half a century: a protocol that makes it possible to expand mouse cells in culture without the cells spontaneously transforming. Amazing though it seems, the secret is simply to grow the cells under hypoxic conditions.
Darwin J Prockop
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-8-22
Journal Detail:
Title:  Cytotherapy     Volume:  -     ISSN:  1477-2566     ISO Abbreviation:  Cytotherapy     Publication Date:  2012 Aug 
Date Detail:
Created Date:  2012-8-22     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100895309     Medline TA:  Cytotherapy     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Department of Medicine, Institute for Regenerative Medicine , Texas A&M University Health Science Center, College of Medicine at Scott & White, Temple, Texas , USA.
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