Document Detail

A literature review of different pressure ulcer models from 1942-2005 and the development of an ideal animal model.
MedLine Citation:
PMID:  18946981     Owner:  NLM     Status:  MEDLINE    
The literature from 1942-2005 was reviewed in order to determine an inexpensive animal model which can closely mimic pressure ulcers seen in humans of varying ages, without the need for surgical procedures. Two animal models for producing pressure ulcers were found to be inexpensive: pigs to mimic pressure ulcers in young humans due to their fixed skin, and rats to mimic pressure ulcers in the elderly due to their loose skin. The methods which were found to be inexpensive, reproducible, non-invasive and easy to carry out without the need of a surgeon or specialist were the use of magnets for rat models and the use of a cast placed over a bony prominence for pig models.
P K T Nguyen; A L Smith; K J Reynolds
Publication Detail:
Type:  Journal Article; Review; Technical Report    
Journal Detail:
Title:  Australasian physical & engineering sciences in medicine / supported by the Australasian College of Physical Scientists in Medicine and the Australasian Association of Physical Sciences in Medicine     Volume:  31     ISSN:  0158-9938     ISO Abbreviation:  Australas Phys Eng Sci Med     Publication Date:  2008 Sep 
Date Detail:
Created Date:  2008-10-24     Completed Date:  2008-11-25     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8208130     Medline TA:  Australas Phys Eng Sci Med     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  223-5     Citation Subset:  IM    
School of Informatics and Engineering, Flinders University, Adelaide, Australia.
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MeSH Terms
Disease Models, Animal*
Pressure Ulcer / diagnosis*,  physiopathology*
Skin / physiopathology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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