Document Detail

The lipid composition of muscle cells during development.
MedLine Citation:
PMID:  563243     Owner:  NLM     Status:  MEDLINE    
Developmental changes in the phospholipid, cholesterol, and fatty acid composition of chicken pectoralis muscle cells were analyzed during development in vivo and in tissue culture. The phospholipid composition of muscle cells showed only minor changes during in vivo or in vitro development but there were significant alterations in fatty acid composition. During in vivo development between the 12th and 22nd days the concentration of palmitate and arachidonate decreased with increase in linoleate. In cultured muscle cells the fatty acid composition changes with surprising plasticity depending on the fatty acid supply. Compensatory changes were observed in the chain length and unsaturation of several fatty acids, aimed presumably at maintaining the physical properties of the lipid phase relatively constant.
R Boland; T Chyn; D Roufa; E Reyes; A Martonosi
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Biochimica et biophysica acta     Volume:  489     ISSN:  0006-3002     ISO Abbreviation:  Biochim. Biophys. Acta     Publication Date:  1977 Dec 
Date Detail:
Created Date:  1978-02-18     Completed Date:  1978-02-18     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0217513     Medline TA:  Biochim Biophys Acta     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  349-59     Citation Subset:  IM    
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MeSH Terms
Chick Embryo
Culture Media
Culture Techniques
Fatty Acids / metabolism
Lipid Metabolism*
Muscle Development*
Muscles / metabolism
Phospholipids / metabolism
Phosphoproteins / metabolism
Sarcoplasmic Reticulum / metabolism
Reg. No./Substance:
0/Culture Media; 0/Fatty Acids; 0/Liposomes; 0/Phospholipids; 0/Phosphoproteins

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