| The linguistic and cognitive profile of Down syndrome: evidence from a comparison with fragile X syndrome. | |
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MedLine Citation:
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PMID: 11706811 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In this paper, we report on the results of our research, which is designed to address two broad questions about the cognitive and linguistic profile of Down syndrome: (1) Which domains of functioning are especially impaired in individuals with Down syndrome? and (2) Which aspects of the language and cognitive profile of Down syndrome are syndrome specific? To address these questions, we focused on three dimensions of the Down syndrome profile--receptive language, expressive language, and theory of mind--and made comparisons to individuals with fragile X syndrome, which is an X-linked form of intellectual disability. We identified Down syndrome impairments on all three dimensions that were substantially greater than those seen in nonverbal cognition and that were not shared by individuals with fragile X syndrome. Clinical implications of these findings are considered. |
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Authors:
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L Abbeduto; M Pavetto; E Kesin; M D Weissman; S Karadottir; A O'Brien; S Cawthon |
Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Down's syndrome, research and practice : the journal of the Sarah Duffen Centre / University of Portsmouth Volume: 7 ISSN: 0968-7912 ISO Abbreviation: Downs Syndr Res Pract Publication Date: 2001 Oct |
Date Detail:
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Created Date: 2001-11-14 Completed Date: 2002-03-15 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 9508122 Medline TA: Downs Syndr Res Pract Country: England |
Other Details:
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Languages: eng Pagination: 9-15 Citation Subset: IM |
Affiliation:
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Waisman Center, University of Wisconsin-Madison, Madison, Wisconsin, USA. abbeduto@waisman.wisc.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Cognition Disorders
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complications*,
diagnosis Down Syndrome / complications* Fragile X Syndrome / complications* Humans Language Disorders / complications*, diagnosis Linguistics* Neuropsychological Tests Severity of Illness Index |
| Grant Support | |
ID/Acronym/Agency:
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P30 HD03352/HD/NICHD NIH HHS; R01 HD24356/HD/NICHD NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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