Document Detail


On-line quantification of ventricular function during dobutamine stress echocardiography.
MedLine Citation:
PMID:  1289098     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
To develop an approach for on-line quantification of left ventricular size and function during pharmacological stress testing we employed echocardiographic automatic edge detection via integrated backscatter imaging during dobutamine infusion in 27 patients. Ventricular cavity areas, fractional area change and rate of cavity area change were obtained on-line with instantaneous graphic display of the data. When compared to baseline image data, patients with a normal response exhibited modest (15%) reduction in end-diastolic cavity areas at peak dobutamine level, but marked (33%) reduction in systolic areas yielding a 52% increase in fractional area change (n = 13; P < 0.001). The second group of patients (n = 14) had an abnormal response characterized by limited changes in measured parameters of ventricular function and reduced fractional area change (P < 0.05). On-line quantification during pharmacological stress echocardiography is a promising addition to the test for surveillance and objective instantaneous evaluation of global cardiac responses.
Authors:
J E Pérez; A D Waggoner; V G Dávila-Roman; H Cardona; J G Miller
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  European heart journal     Volume:  13     ISSN:  0195-668X     ISO Abbreviation:  Eur. Heart J.     Publication Date:  1992 Dec 
Date Detail:
Created Date:  1993-03-25     Completed Date:  1993-03-25     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  8006263     Medline TA:  Eur Heart J     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  1669-76     Citation Subset:  IM    
Affiliation:
Cardiovascular Division, Washington University School of Medicine, St Louis, Missouri 63110.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Dobutamine / diagnostic use*
Echocardiography / methods*
Exercise Test
Female
Heart Ventricles / ultrasonography
Humans
Image Processing, Computer-Assisted*
Male
Middle Aged
Myocardial Contraction
Ventricular Function, Left*
Grant Support
ID/Acronym/Agency:
HL-17646/HL/NHLBI NIH HHS; HL-40302/HL/NHLBI NIH HHS
Chemical
Reg. No./Substance:
34368-04-2/Dobutamine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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