Document Detail


The limited access paradigm: description of one method.
MedLine Citation:
PMID:  1418671     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Restricting access to alcohol to a short period daily causes rats, in effect, to drink on command. They usually begin drinking alcohol immediately when it is first made available each day and consume a rather constant amount during each access period. The procedure thus has a variety of useful applications. The specific method reported here in detail provides continual access to food and water, but access to unflavored 10% ethanol solution only 1 h/d, all in the home cage, and produces mean alcohol intakes from 0.5-1.0 g/kg in the access hour.
Authors:
J D Sinclair; P Hyytiä; M Nurmi
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Alcohol (Fayetteville, N.Y.)     Volume:  9     ISSN:  0741-8329     ISO Abbreviation:  Alcohol     Publication Date:    1992 Sep-Oct
Date Detail:
Created Date:  1992-12-10     Completed Date:  1992-12-10     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  8502311     Medline TA:  Alcohol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  441-4     Citation Subset:  IM    
Affiliation:
Biomedical Research Center, Alko Ltd., Helsinki, Finland.
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MeSH Terms
Descriptor/Qualifier:
Alcohol Drinking*
Animals
Male
Methods
Rats
Rats, Wistar

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