Document Detail


A light & electron microscopic study on apoptotic bodies in acute aflatoxin B1 induced injury in the rat liver.
MedLine Citation:
PMID:  1908823     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A subnecrogenic dose of aflatoxin B1 (AFB1) was injected intraperitoneally into 8-10 wk old male rats of the Holzman strain. Cytoplasmic and sinusoidal eosinophilic bodies were seen in the liver which appeared at 30 h and reached a maximum at 48 h. Electron microscopically some of the cytoplasmic structures were seen to be of mitochondrial origin whereas others resembled apoptotic bodies. The sinusoidal bodies were similar to apoptotic bodies.
Authors:
S Bose; M Mathur; N C Nayak
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Indian journal of medical research     Volume:  94     ISSN:  0971-5916     ISO Abbreviation:  Indian J. Med. Res.     Publication Date:  1991 Apr 
Date Detail:
Created Date:  1991-10-02     Completed Date:  1991-10-02     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0374701     Medline TA:  Indian J Med Res     Country:  INDIA    
Other Details:
Languages:  eng     Pagination:  134-8     Citation Subset:  IM    
Affiliation:
Department of Pathology, All India Institute of Medical Sciences, New Delhi.
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MeSH Terms
Descriptor/Qualifier:
Aflatoxin B1
Aflatoxins / pharmacology*
Animals
Cell Degranulation
Cell Survival / drug effects
Cytoplasmic Granules / ultrastructure*
Liver / drug effects,  ultrastructure*
Male
Microscopy, Electron
Rats
Rats, Inbred Strains
Chemical
Reg. No./Substance:
0/Aflatoxins; 1162-65-8/Aflatoxin B1

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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