Document Detail


The level of blood kinins, their creation and inactivation after one exposure to intense ultraviolet radiation in rabbits.
MedLine Citation:
PMID:  6272547     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Experimental rabbits were exposed to ultraviolet radiation once for 45 minutes, and blood samples were obtained from the carotid artery in these animals 45 min and 3, 6 and 24 hours after the end of this exposure. In the group of control rabbits blood samples were obtained in the same way without previous exposure to radiation. The hairs on the back were cut closely at the skin and this skin area was exposed to ultraviolet rays from a Hanau Q 400 burner at 405--289 nm wavelengths and at an intensity of 134 000 erg/sec/cm2, using an UG 2 T Schott filtre and an absorber of long-wave radiation. Blood samples were taken under thiopental anaesthesia. In the samples the level of free kinins was determined in the blood, and the level of kininogen and the activity of kallikreins and kininases were determined in the plasma. In the irradiated animals a rise of the kinin level was observed, with a fall in the kininogen level most pronounced after 3 hours, while the activity of kallikreins was raised and that of kininases was decreased particularly after 6 hours.
Authors:
B Legiecka
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Acta physiologica Polonica     Volume:  32     ISSN:  0044-6033     ISO Abbreviation:  Acta Physiol Pol     Publication Date:    1981 May-Jun
Date Detail:
Created Date:  1982-01-20     Completed Date:  1982-01-20     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  2985166R     Medline TA:  Acta Physiol Pol     Country:  POLAND    
Other Details:
Languages:  eng     Pagination:  247-53     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Enzyme Inhibitors
Kallikreins / blood,  radiation effects
Kinins / blood,  radiation effects*
Lysine Carboxypeptidase / blood,  radiation effects
Male
Peptidyl-Dipeptidase A / blood,  radiation effects
Rabbits
Radiation Dosage
Time Factors
Ultraviolet Rays*
Chemical
Reg. No./Substance:
0/Enzyme Inhibitors; 0/Kinins; EC 3.4.15.1/Peptidyl-Dipeptidase A; EC 3.4.17.3/Lysine Carboxypeptidase; EC 3.4.21.-/Kallikreins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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