| The leukotriene receptor antagonist montelukast and aortic stenosis. | |
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MedLine Citation:
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PMID: 22616719 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Aortic stenosis shares several characteristics with atherosclerotic lesions, such as inflammation and lipid accumulation leading to extensive calcification of the valvular leaflets, which eventually causes the aortic valve to narrow [1]. However, lipid-lowering drugs of the statin class have not been shown to retard the progression of aortic stenosis. In fact, to date there is no medical treatment for this valvular heart disease, and aortic stenosis remains the most common indication for surgical valve replacement [1]. © 2012 The Authors. British Journal of Clinical Pharmacology © 2012 The British Pharmacological Society. |
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Authors:
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Magnus Bäck; Li Yin; Edit Nagy; Erik Ingelsson |
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Publication Detail:
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Type: LETTER Date: 2012-5-23 |
Journal Detail:
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Title: British journal of clinical pharmacology Volume: - ISSN: 1365-2125 ISO Abbreviation: - Publication Date: 2012 May |
Date Detail:
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Created Date: 2012-5-23 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7503323 Medline TA: Br J Clin Pharmacol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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© 2012 The Authors. British Journal of Clinical Pharmacology © 2012 The British Pharmacological Society. |
Affiliation:
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Department of Medicine, Karolinska Institutet, Department of Cardiology, Karolinska University Hospital, Department of Medical Epidemiology & Biostatistics, Karolinska Institutet, Stockholm, Sweden. |
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