Document Detail


A lethal association of congenital apnea with brainstem tegmental necrosis.
MedLine Citation:
PMID:  15033208     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We present a female with premature birth, polyhydramnios, congenital apnea, cranial nerve palsies, orofacial and limb anomalies. Neuroimaging revealed calcifications along the vental margin of the caudal fourth ventricle. Neuropathologic findings at postmortem examination were consistent with brainstem tegmental necrosis and olivary hypoplasia, a rare lethal entity that should be considered in the differential diagnosis of congenital apnea.
Authors:
Martin P Moya; G Robert Delong; Daniel Barboriak; Thomas J Cummings
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Pediatric neurology     Volume:  30     ISSN:  0887-8994     ISO Abbreviation:  Pediatr. Neurol.     Publication Date:  2004 Mar 
Date Detail:
Created Date:  2004-03-22     Completed Date:  2004-08-03     Revised Date:  2006-05-23    
Medline Journal Info:
Nlm Unique ID:  8508183     Medline TA:  Pediatr Neurol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  219-21     Citation Subset:  IM    
Affiliation:
Department of Pediatrics, Duke University Medical Center, Durham, North Carolina, USA.
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MeSH Terms
Descriptor/Qualifier:
Abnormalities, Multiple / diagnosis*,  pathology
Apnea / congenital*,  pathology
Brain Stem / pathology*
Calcinosis / congenital,  diagnosis,  pathology
Cerebral Hemorrhage / diagnosis,  pathology
Cerebral Ventricles / pathology
Deafness / congenital,  diagnosis
Diagnosis, Differential
Echoencephalography
Fatal Outcome
Female
Humans
Infant, Newborn
Necrosis
Olivary Nucleus / abnormalities,  pathology
Sex Factors
Tegmentum Mesencephali / pathology*
Tomography, X-Ray Computed

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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