| Is left ventricular hypertrophy a risk factor in hypertensive patients? | |
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MedLine Citation:
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PMID: 12448569 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Left ventricular hypertrophy (LVH) is supposed to be a risk factor of cardiovascular (CV) complications in hypertensive patients. AIM: To compare clinical events in hypertensives with and without LVH. PATIENTS AND METHODS: 319 hypertensives with LVH (mean age 64.1+/-10.6 ys) and 177 hypertensives without LVH (mean age 62.5+/-11.3 ys). LVH defined by echo Penn convention as left ventricular mass index >134 g/m2 in men and >110 g/m2 in women. Clinical events--heart failure (EF<40 %), left ventricular diastolic dysfunction (echo-doppler: transmitral-flow where peak A>peak E), myocardial infarction (history, ECG, cardiac enzymes), chronic atrial fibrillation (more than 2 weeks duration), mitral regurgitation (echo) and renal involvement (creatininemia>120 micromol/l). The two groups of hypertensives were matched by demographic criteria, duration and intensity of hypertension, obesity, diabetes mellitus, lipid serum levels and smoking habits. RESULTS: There were statistically significant at least p<0.05 more CV events (heart failure, left ventricular diastolic dysfunction, myocardial infarction, chronic atrial fibrillation, and mitral regurgitation cases) and renal involvement in LVH-positive patients than in LVH-negative patients. CONCLUSION: LVH is a strong risk factor for clinical events in hypertensives, which necessitates their more intensive treatment, mainly with drugs producing also LVH regression. (Tab. 5, Ref. 48.) |
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Authors:
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Wisam M A Ghanem; J Murin; O Sleiman; J Bulas; J Jaber; P Mikes; L Baqi; A Radman; K Kozlikova; A Reptova |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Bratislavské lekárske listy Volume: 103 ISSN: 0006-9248 ISO Abbreviation: Bratisl Lek Listy Publication Date: 2002 |
Date Detail:
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Created Date: 2002-11-22 Completed Date: 2002-12-12 Revised Date: 2009-11-11 |
Medline Journal Info:
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Nlm Unique ID: 0065324 Medline TA: Bratisl Lek Listy Country: Slovakia |
Other Details:
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Languages: eng Pagination: 215-22 Citation Subset: IM |
Affiliation:
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1st Internal Department, University Hospital, Comenius University, Bratislava, Slovakia. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Female Humans Hypertension / complications*, drug therapy Hypertrophy, Left Ventricular / diagnosis, etiology* Male Middle Aged Retrospective Studies Risk Factors |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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