| The laser driven heating balloon catheter: vessel dilatation characteristics. | |
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MedLine Citation:
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PMID: 19163504 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We studied on the dilatation characteristics of our new angioplasty, photo-thermo dynamic balloon (PTDB) angioplasty, which provides short-term heating (15s, 50-70 degrees C) dilatation by the combination of laser heat generator and fluid perfusion. In this study, we employed the ex vivo experiments to demonstrate the feasibility of our PTDB angioplasty with extracted porcine carotid artery. Balloon temperature and heating duration were easily controlled with the laser power and irradiation duration. Arterial dilatation was performed with the prototype PTDB catheter (3mm in diameter) ex vivo, sufficient dilation was attained with low dilatation pressure (2atm) that is lower than the limit pressure of elastic region (8atm in this case). The principal of our PTDB angioplasty that was based on the experimental results was dilatation in elastic region, while traditional POBA was accompanied with plastic deformation of artery. It is predicted that successful way of PTDB dilatation was attributed to collagen softening. Collagen coagulation and/or restructure after the heating dilatation might suspend the dilated arterial lumen. We demonstrated the feasibility of our PTDB angioplasty. We think collagen denaturation degree may be the important factor in this methodology. |
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Authors:
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Natsumi Shimazaki; Go Mizukami; Hisako Tokunaga; Kenji Kaneko; Tsunenori Arai |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference Volume: 2008 ISSN: 1557-170X ISO Abbreviation: Conf Proc IEEE Eng Med Biol Soc Publication Date: 2008 |
Date Detail:
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Created Date: 2009-02-16 Completed Date: 2009-05-11 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101243413 Medline TA: Conf Proc IEEE Eng Med Biol Soc Country: United States |
Other Details:
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Languages: eng Pagination: 3661-3 Citation Subset: IM |
Affiliation:
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School of Fundamental Science and Technology, Graduate School of Science and Technology, KEIO University, Japan. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Algorithms Angioplasty, Transluminal, Percutaneous Coronary / instrumentation, methods* Animals Carotid Arteries / pathology* Catheterization* Collagen / chemistry Coronary Angiography / methods Equipment Design Hot Temperature Lasers* Phototherapy / methods Pressure Reproducibility of Results Temperature Time Factors |
| Chemical | |
Reg. No./Substance:
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9007-34-5/Collagen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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