| The laryngeal and esophageal manifestations of Sjögren's syndrome. | |
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MedLine Citation:
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PMID: 14531957 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Laryngopharyngeal reflux (LPR) is the syndrome caused by the backflow of gastric contents into the upper aerodigestive tract. Acid and pepsin in the pharynx, larynx, oral cavity, and trachea have been associated with dysphonia, chronic cough, reactive airway disease, middle ear effusion, throat pain, excessive throat mucus, postnasal drip, dental caries, and laryngeal cancer. The symptoms of LPR frequently occur in the absence of heartburn and esophagitis, and, thus, the diagnosis may be elusive. Individuals with Sjögren's syndrome are predisposed to reflux, and a high index of suspicion for LPR must be maintained in all individuals with the disease. This manuscript describes the laryngeal, pharyngeal, and esophageal manifestations of reflux in patients with Sjögren's syndrome and reviews state-of-the-art diagnostic and treatment strategies. |
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Authors:
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Peter C Belafsky; Gregory N Postma |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Current rheumatology reports Volume: 5 ISSN: 1523-3774 ISO Abbreviation: Curr Rheumatol Rep Publication Date: 2003 Aug |
Date Detail:
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Created Date: 2003-10-08 Completed Date: 2004-01-06 Revised Date: 2005-11-16 |
Medline Journal Info:
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Nlm Unique ID: 100888970 Medline TA: Curr Rheumatol Rep Country: United States |
Other Details:
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Languages: eng Pagination: 297-303 Citation Subset: IM |
Affiliation:
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Scripps Center for Voice and Swallowing, 9888 Genesee Avenue, #128, La Jolla, CA 92037, USA. pcb@san.rr.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Esophagoscopy Esophagus / physiopathology* Gastroesophageal Reflux / etiology Humans Larynx / physiopathology* Otorhinolaryngologic Diseases / etiology*, physiopathology Pharynx / physiopathology* Sjogren's Syndrome / complications*, physiopathology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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