Document Detail


A large-scale, orthogonal network of microfibril bundles in the corneal stroma.
MedLine Citation:
PMID:  3119511     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Orthogonal and parallel arrays of microfibril bundles are described in the corneal stroma of embryonic and adult chickens. The arrays lie parallel to the corneal surface and are distributed in the extracellular matrix between Bowman's layer and Descemet's membrane. The individual microfibril bundles measure 0.1-0.25 micron in diameter and consist of 20-30 "tubular" rods, of approximately 15 nm diameter, and an apparently structureless matrix. The arrays have a spacing of approximately 3 microns. We speculate that the microfibril bundles serve as a scaffolding for the corneal stroma or as a light-diffracting element. With some variations in distribution and organization, the arrays of microfibril bundles also occur in calf, rabbit, rat, newborn mice, toad, and goldfish, but not in adult human corneas.
Authors:
R R Bruns; W Press; J Gross
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Investigative ophthalmology & visual science     Volume:  28     ISSN:  0146-0404     ISO Abbreviation:  Invest. Ophthalmol. Vis. Sci.     Publication Date:  1987 Dec 
Date Detail:
Created Date:  1988-01-19     Completed Date:  1988-01-19     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  7703701     Medline TA:  Invest Ophthalmol Vis Sci     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1939-46     Citation Subset:  IM    
Affiliation:
Department of Medicine, Massachusetts General Hospital, Boston 02114.
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MeSH Terms
Descriptor/Qualifier:
Aged
Animals
Bufo marinus
Cattle
Chick Embryo
Chickens
Collagen / analysis
Cornea / ultrastructure*
Corneal Stroma / analysis,  ultrastructure*
Female
Goldfish
Humans
Mice
Rabbits
Rats
Rats, Inbred Strains
Species Specificity
Grant Support
ID/Acronym/Agency:
AM-3564/AM/NIADDK NIH HHS
Chemical
Reg. No./Substance:
9007-34-5/Collagen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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