Document Detail


The lactate paradox in human high-altitude physiological performance.
MedLine Citation:
PMID:  12021383     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
For many years, physiologists have puzzled over the observation that, during maximum aerobic exercise, high-altitude natives generate lower-than-expected amounts of lactate; the higher the altitude, the lower the postexercise blood lactate peak. This paradoxical situation may be caused mainly by upregulated metabolic control contributions from cell ATP demand and ATP supply pathways.
Authors:
P W Hochachka; C L Beatty; Y Burelle; M E Trump; D C McKenzie; G O Matheson
Related Documents :
2353853 - The coronary stress of skiing at high altitude.
15947723 - Altitude negates the benefits of aerobic training on the vascular adaptations in rats.
7801833 - Circulatory function during exercise: integration of convection and diffusion.
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society     Volume:  17     ISSN:  0886-1714     ISO Abbreviation:  News Physiol. Sci.     Publication Date:  2002 Jun 
Date Detail:
Created Date:  2002-05-21     Completed Date:  2002-07-16     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8609378     Medline TA:  News Physiol Sci     Country:  United States    
Other Details:
Languages:  eng     Pagination:  122-6     Citation Subset:  IM    
Affiliation:
Department of Zoology, University of British Columbia, Vancouver, British Columbia V6T 1Z4, Canada.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Acclimatization / physiology*
Altitude*
Exercise / physiology*
Humans
Lactic Acid / blood*
Chemical
Reg. No./Substance:
50-21-5/Lactic Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Metabolic diseases: the environment determines the odds, even for genes.
Next Document:  Quantitation of mRNAs for M(1) to M(5) subtypes of muscarinic receptors in rat heart and brain corte...