Document Detail

The lactate paradox in human high-altitude physiological performance.
MedLine Citation:
PMID:  12021383     Owner:  NLM     Status:  MEDLINE    
For many years, physiologists have puzzled over the observation that, during maximum aerobic exercise, high-altitude natives generate lower-than-expected amounts of lactate; the higher the altitude, the lower the postexercise blood lactate peak. This paradoxical situation may be caused mainly by upregulated metabolic control contributions from cell ATP demand and ATP supply pathways.
P W Hochachka; C L Beatty; Y Burelle; M E Trump; D C McKenzie; G O Matheson
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society     Volume:  17     ISSN:  0886-1714     ISO Abbreviation:  News Physiol. Sci.     Publication Date:  2002 Jun 
Date Detail:
Created Date:  2002-05-21     Completed Date:  2002-07-16     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8609378     Medline TA:  News Physiol Sci     Country:  United States    
Other Details:
Languages:  eng     Pagination:  122-6     Citation Subset:  IM    
Department of Zoology, University of British Columbia, Vancouver, British Columbia V6T 1Z4, Canada.
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MeSH Terms
Acclimatization / physiology*
Exercise / physiology*
Lactic Acid / blood*
Reg. No./Substance:
50-21-5/Lactic Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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