| The laboratory school protocol: its origin, use, and new applications. | |
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MedLine Citation:
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PMID: 16840597 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: ADHD is the most common childhood psychiatric disorder, with impairments seen in home and academic settings. To investigate such impairments in a school-like setting, the laboratory school protocol (LSP) was developed at the University of California, Irvine. METHOD: This model provides a rigorously controlled environment to examine pharmacodynamic and pharmacokinetic aspects of responses to treatment. A key principle of this methodology is to exercise tight control of the timing and context of measurements by establishing a cycle of activities repeated across each study day. In addition, the LSP approach has been extended to both younger and older populations than the typically studied school-aged group. This extension requires corresponding modifications in measures to characterize drug efficacy and to allow evaluation of ADHD symptoms in a highly standardized setting. RESULTS: This article provides guidelines for employing the LSP for the assessment of medication effects for both preschool and adolescent/adult populations. CONCLUSION: The LSP can be modified to form either an Adult Workplace Environment or a Preschool Assessment Laboratory. |
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Authors:
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Sharon B Wigal; Timothy L Wigal |
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Publication Detail:
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Type: Clinical Trial; Journal Article |
Journal Detail:
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Title: Journal of attention disorders Volume: 10 ISSN: 1087-0547 ISO Abbreviation: J Atten Disord Publication Date: 2006 Aug |
Date Detail:
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Created Date: 2006-07-14 Completed Date: 2006-10-03 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9615686 Medline TA: J Atten Disord Country: Canada |
Other Details:
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Languages: eng Pagination: 92-111 Citation Subset: IM |
Affiliation:
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University of California, Irvine, Child Development Center, CA 92612, USA. sbwigal@uci.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Attention Deficit Disorder with Hyperactivity
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drug therapy* Central Nervous System Stimulants / pharmacology*, therapeutic use* Child Child, Preschool Cognition / drug effects Humans Psychomotor Performance / drug effects* Reaction Time / drug effects School Health Services* |
| Chemical | |
Reg. No./Substance:
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0/Central Nervous System Stimulants |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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