Document Detail


The kidney in pregnancy: A journey of three decades.
MedLine Citation:
PMID:  23087548     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
The spectrum of kidney disease occurring during pregnancy includes preeclampsia, hypertensive disorders of pregnancy, urinary tract infection, acute kidney injury, and renal cortical necrosis (RCN). Preeclampsia affects approximately 3-5% of pregnancies. We observed preeclampsia in 5.8% of pregnancies, and 2.38% of our preeclamptic women developed eclampsia. Severe preeclampsia and the eclampsia or hemolysis, elevated liver enzymes levels, and low platelets count (HELLP) syndrome accounted for about 40% of cases of acute kidney injury (AKI) in pregnancy. Preeclampsia/eclampsia was the cause of acute renal failure (ARF) in 38.3% of the cases. Preeclampsia was the most common (91.7%) cause of hypertension during pregnancy, and chronic hypertension was present in 8.3% of patients. We observed urinary tract infection (UTI) in 9% of pregnancies. Sepsis resulting from pyelonephritis can progress to endotoxic shock, disseminated intravascular coagulation, and AKI. The incidence of premature delivery and low birth weight is higher in women with UTI. The incidence of AKI in pregnancy with respect to total ARF cases has decreased over the last 30 years from 25% in 1980s to 5% in 2000s. Septic abortion-related ARF decreased from 9% to 3%. Prevention of unwanted pregnancy and avoidance of septic abortion are key to eliminate abortion-associated ARF in early pregnancy. The two most common causes of ARF in third trimester and postpartum periods were puerperal sepsis and preeclampsia/HELLP syndrome. Pregnancy-associated thrombotic thrombocytopenic purpura/hemolytic uremic syndrome and acute fatty liver of pregnancy were rare causes of ARF. Despite decreasing incidence, AKI remains a serious complication during pregnancy.
Authors:
J Prakash
Related Documents :
15150078 - Autoantibodies against epcr are found in antiphospholipid syndrome and are a risk facto...
10778558 - The prevalence of antiphospholipid antibodies in cases of recurrent pregnancy loss.
23563878 - Peripheral nerve disease in pregnancy.
12492708 - Pregnancy outcomes in female renal recipients: a comparison of systemic lupus erythemat...
22814658 - The current state of therapeutic drug trials in pregnancy.
23470108 - Examining caesarean section rates in canada using the robson classification system.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Indian journal of nephrology     Volume:  22     ISSN:  1998-3662     ISO Abbreviation:  Indian J Nephrol     Publication Date:  2012 May 
Date Detail:
Created Date:  2012-10-22     Completed Date:  2012-10-23     Revised Date:  2013-05-30    
Medline Journal Info:
Nlm Unique ID:  8914356     Medline TA:  Indian J Nephrol     Country:  India    
Other Details:
Languages:  eng     Pagination:  159-67     Citation Subset:  -    
Affiliation:
Department of Nephrology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Fighting fair: Adaptive Marital Conflict Strategies as Predictors of Future Adolescent Peer and Roma...
Next Document:  Effect of short-term intravenous ascorbic acid on reducing ferritin in hemodialysis patients.