Document Detail

The kidney, hypertension, and remaining challenges.
MedLine Citation:
PMID:  19427500     Owner:  NLM     Status:  MEDLINE    
There is an epidemic of chronic kidney disease in the Western world, with hypertension being the second most common cause. Blood pressure control rates, while improving, are still below 50% for the United States population. The following three challenges remain for the treatment of hypertension and associated prevention of end-stage kidney disease. First, a better understanding by the general medical community of how and in whom to use renin angiotensin aldosterone system blockers is needed. Second, the appropriate initiation of fixed-dose combination therapy to achieve blood-pressure goals needs to be clarified. Finally, the subgroup of patients with kidney disease needs more aggressive blood pressure lowering.
Nitin Khosla; Rigas Kalaitzidis; George L Bakris
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  The Medical clinics of North America     Volume:  93     ISSN:  1557-9859     ISO Abbreviation:  Med. Clin. North Am.     Publication Date:  2009 May 
Date Detail:
Created Date:  2009-05-11     Completed Date:  2009-06-09     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  2985236R     Medline TA:  Med Clin North Am     Country:  United States    
Other Details:
Languages:  eng     Pagination:  697-715, Table of Contents     Citation Subset:  AIM; IM    
Department of Medicine, Section of Nephrology and Hypertension, University of California at San Diego, San Diego, CA, USA.
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MeSH Terms
Antihypertensive Agents / pharmacology,  therapeutic use
Blood Pressure / drug effects
Hypertension, Renovascular / complications,  drug therapy*,  epidemiology
Kidney / drug effects*
Kidney Failure, Chronic / epidemiology,  etiology,  prevention & control*
Renin-Angiotensin System / drug effects
United States / epidemiology
Reg. No./Substance:
0/Antihypertensive Agents

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