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The ketogenic diet for type II bipolar disorder.
MedLine Citation:
PMID:  23030231     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Successful mood stabilizing treatments reduce intracellular sodium in an activity-dependent manner. This can also be achieved with acidification of the blood, as is the case with the ketogenic diet. Two women with type II bipolar disorder were able to maintain ketosis for prolonged periods of time (2 and 3 years, respectively). Both experienced mood stabilization that exceeded that achieved with medication; experienced a significant subjective improvement that was distinctly related to ketosis; and tolerated the diet well. There were no significant adverse effects in either case. These cases demonstrate that the ketogenic diet is a potentially sustainable option for mood stabilization in type II bipolar illness. They also support the hypothesis that acidic plasma may stabilize mood, perhaps by reducing intracellular sodium and calcium.
Authors:
James R Phelps; Susan V Siemers; Rif S El-Mallakh
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-10-3
Journal Detail:
Title:  Neurocase     Volume:  -     ISSN:  1465-3656     ISO Abbreviation:  Neurocase     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-10-3     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9511374     Medline TA:  Neurocase     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
a PsychEducation.org and Samaritan Mental Health , Corvallis , OR , USA.
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