Document Detail


The joy of six: how to control your crossovers.
MedLine Citation:
PMID:  22464316     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
Meiotic cells tightly regulate the number and distribution of crossovers to promote accurate chromosome segregation. Yokoo and colleagues uncover a metazoan-specific, cyclin-like protein that is crucial for crossover formation. They utilize this protein's unique properties to explore a remarkable example of biological numerology, whereby nearly every meiotic cell in C. elegans makes precisely six crossovers, one for each of its six chromosome pairs.
Authors:
Samuel T Globus; Scott Keeney
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Publication Detail:
Type:  Comment; Journal Article    
Journal Detail:
Title:  Cell     Volume:  149     ISSN:  1097-4172     ISO Abbreviation:  Cell     Publication Date:  2012 Mar 
Date Detail:
Created Date:  2012-04-02     Completed Date:  2012-06-04     Revised Date:  2013-01-16    
Medline Journal Info:
Nlm Unique ID:  0413066     Medline TA:  Cell     Country:  United States    
Other Details:
Languages:  eng     Pagination:  11-2     Citation Subset:  -    
Copyright Information:
Copyright © 2012 Elsevier Inc. All rights reserved.
Affiliation:
Molecular Biology Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.
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MeSH Terms
Descriptor/Qualifier:
Grant Support
ID/Acronym/Agency:
R01 GM058673/GM/NIGMS NIH HHS
Comments/Corrections
Comment On:
Cell. 2012 Mar 30;149(1):75-87   [PMID:  22464324 ]

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