Document Detail

The itchy scalp--scratching for an explanation.
MedLine Citation:
PMID:  22092575     Owner:  NLM     Status:  MEDLINE    
Scalp pruritus is a common complaint that is considered a diagnostically and therapeutically challenging situation. Scalp skin has a unique neural structure that contains densely innervated hair follicles and dermal vasculature. In spite of the recent advances in our understanding of itch pathophysiology, scalp itching has not been studied as yet. In this review, we summarize the current knowledge on the neurobiology of scalp and hair follicles as well as itch mediators and provide a putative mechanism for scalp itch with special emphasis on neuroanatomy and pathophysiology.
Ghada A Bin Saif; Marna E Ericson; Gil Yosipovitch
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Review    
Journal Detail:
Title:  Experimental dermatology     Volume:  20     ISSN:  1600-0625     ISO Abbreviation:  Exp. Dermatol.     Publication Date:  2011 Dec 
Date Detail:
Created Date:  2011-11-18     Completed Date:  2012-05-11     Revised Date:  2014-09-11    
Medline Journal Info:
Nlm Unique ID:  9301549     Medline TA:  Exp Dermatol     Country:  Denmark    
Other Details:
Languages:  eng     Pagination:  959-68     Citation Subset:  IM    
Copyright Information:
© 2011 John Wiley & Sons A/S.
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MeSH Terms
Pruritus / drug therapy,  etiology*,  metabolism,  microbiology,  physiopathology*
Scalp / innervation*,  metabolism,  microbiology,  physiopathology*
Sebum / metabolism
Grant Support
R0-1AR55902-3/AR/NIAMS NIH HHS; R01 AR055902/AR/NIAMS NIH HHS; R01 AR055902-03/AR/NIAMS NIH HHS; R01AR055902-03A1./AR/NIAMS NIH HHS

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