| Is it time to abandon the use of amphotericin B bladder irrigation? | |
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MedLine Citation:
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PMID: 15844069 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In this article, we review the issues surrounding funguria and its management. With this background, the value of bladder irrigation with amphotericin B for the management of funguria is directly examined. Amphotericin B bladder irrigation is used frequently in clinical practice. Although its use is not standardized, there are multiple studies that attempt to show the impact on funguria management. These bladder irrigations have been used either for treatment of funguria or (less commonly) as a diagnostic test in attempts to identify upper urinary tract disease. Despite their widespread therapeutic use and relative safety, it is not clear from our experience and a review of the literature that amphotericin B bladder irrigations have any diagnostic or therapeutic value. The patient may be best served by removal of the urinary catheter, if possible, rather than by instillation of bladder irrigation with amphotericin B. |
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Authors:
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Richard H Drew; Rebekah R Arthur; John R Perfect |
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Publication Detail:
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Type: Journal Article; Review Date: 2005-03-29 |
Journal Detail:
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Title: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America Volume: 40 ISSN: 1537-6591 ISO Abbreviation: Clin. Infect. Dis. Publication Date: 2005 May |
Date Detail:
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Created Date: 2005-04-21 Completed Date: 2006-06-28 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9203213 Medline TA: Clin Infect Dis Country: United States |
Other Details:
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Languages: eng Pagination: 1465-70 Citation Subset: IM |
Affiliation:
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Campbell University School of Pharmacy, Buies Creek, North Carolina, USA. richard.drew@duke.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Amphotericin B
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therapeutic use* Antifungal Agents / therapeutic use* Humans Mycoses / drug therapy*, microbiology Urinary Catheterization* Urinary Tract Infections / drug therapy*, microbiology |
| Chemical | |
Reg. No./Substance:
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0/Antifungal Agents; 1397-89-3/Amphotericin B |
| Comments/Corrections | |
Comment In:
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Clin Infect Dis. 2005 Oct 1;41(7):1073-4; author reply 1074
[PMID:
16142684
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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