Document Detail

Is it safe to use inhaled corticosteroids in pregnancy?
MedLine Citation:
PMID:  25217675     Owner:  NLM     Status:  In-Data-Review    
QUESTION: A healthy woman with mild to moderate asthma came to my clinic today after learning that she was pregnant. She inquired about continuing her inhaled corticosteroid (ICS) medication and whether there would be any risks to her unborn child if she were to do so. What would you advise?
ANSWER: Given the published evidence, ICSs should be continued throughout pregnancy at low to moderate doses sufficient to control asthma symptoms and prevent exacerbations. However, caution must be taken with doses greater than 1000 µg/d (chlorofluorocarbon beclomethasone equivalent), although whether such doses cause adverse effects is currently still questionable. Patient education on proper ICS administration and adherence, including during the first trimester, must be ongoing. Well controlled asthma will reduce the need for higher ICS doses and possible exposure to systemic corticosteroids, and might decrease the risk of adverse pregnancy or perinatal outcomes.
Laura Smy; Alvin C H Chan; Pina Bozzo; Gideon Koren
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Canadian family physician Médecin de famille canadien     Volume:  60     ISSN:  1715-5258     ISO Abbreviation:  Can Fam Physician     Publication Date:  2014 Sep 
Date Detail:
Created Date:  2014-09-13     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0120300     Medline TA:  Can Fam Physician     Country:  Canada    
Other Details:
Languages:  eng     Pagination:  809-12     Citation Subset:  IM    
Copyright Information:
Copyright© the College of Family Physicians of Canada.
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