Document Detail


The isolation and identification of precursors and reaction products in the clandestine manufacture of methaqualone and mecloqualone.
MedLine Citation:
PMID:  3840834     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Abuse of the hypnotic quinazolinone is well recognized and increasing. Clandestine laboratories producing methaqualone (2-methyl-3-ortho-tolyl-4(3H) quinazolinone) and mecloqualone (2-methyl-3-ortho-chlorophenyl-4(3H) quinazolinone) have been discovered throughout the United States. These laboratories utilize one of many synthesis routes to produce the illicit quinazolinone. Frequently, the clandestine chemist has little, if any, formal education in chemistry; does not keep notes; and does not label flasks and beakers containing solutions. The forensic chemist may be asked to analyze unmarked reaction mixtures that were seized in a clandestine laboratory raid. As a result, a rapid method of isolation and identification of the precursors and products of such a mixture is presented.
Authors:
S A Angelos; J A Meyers
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of forensic sciences     Volume:  30     ISSN:  0022-1198     ISO Abbreviation:  J. Forensic Sci.     Publication Date:  1985 Oct 
Date Detail:
Created Date:  1986-01-09     Completed Date:  1986-01-09     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0375370     Medline TA:  J Forensic Sci     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1022-47     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Chromatography, Gas
Chromatography, High Pressure Liquid
Humans
Methaqualone / chemical synthesis*,  isolation & purification
Quinazolines / chemical synthesis*,  isolation & purification
Chemical
Reg. No./Substance:
0/Quinazolines; 340-57-8/mecloqualone; 72-44-6/Methaqualone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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