Document Detail

Is isolated systolic hypertension worse than combined systolic/diastolic hypertension?
MedLine Citation:
PMID:  23126357     Owner:  NLM     Status:  MEDLINE    
New developments in cardiovascular translational sciences have significantly advanced our understanding of the endovascular biology of blood pressure. Reductions in vascular elasticity and vessel compliance of conduit arteries are key components of both ISH and SDH. Vascular changes from the matrix metalloproteinase family of enzymes are involved in arterial wall remodeling and vascular stiffness. This new translational information helps further our understanding of both ISH and SDH.
Yonggang Ma; Andriy Yabluchanskiy; Merry L Lindsey; Robert J Chilton
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't     Date:  2012-10-09
Journal Detail:
Title:  Journal of clinical hypertension (Greenwich, Conn.)     Volume:  14     ISSN:  1751-7176     ISO Abbreviation:  J Clin Hypertens (Greenwich)     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2012-11-06     Completed Date:  2013-04-30     Revised Date:  2014-05-27    
Medline Journal Info:
Nlm Unique ID:  100888554     Medline TA:  J Clin Hypertens (Greenwich)     Country:  United States    
Other Details:
Languages:  eng     Pagination:  808-9     Citation Subset:  IM    
Copyright Information:
© 2012 Wiley Periodicals, Inc.
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MeSH Terms
Diastole / physiology*
Endothelium, Vascular / physiopathology*
Hypertension / physiopathology*
Matrix Metalloproteinase 9 / physiology
Systole / physiology*
Translational Medical Research
Vascular Calcification / physiopathology
Grant Support
HHSN268201000036C/HL/NHLBI NIH HHS; I01 BX000505/BX/BLRD VA; N01-HV-00244/HV/NHLBI NIH HHS; NIH ⁄ NHLBI HHSN 268201000036C//PHS HHS; R01 HL075360/HL/NHLBI NIH HHS; R01HL075360/HL/NHLBI NIH HHS
Reg. No./Substance:
EC Metalloproteinase 9

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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