| An isolated hand tumour as primary manifestation of sarcoidosis. | |
| | |
MedLine Citation:
|
PMID: 21796894 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
|
BACKGROUND: Sarcoidosis is a systemic disorder with unknown etiology, characterized by non-caseating granulomas in numerous organs and tissues. In 90% of patients lung and lymph nodes are involved. The incidence of sarcoidal granulomas in the upper extremities is low. Here we present the case of a primary hand manifestation of sarcoidosis without clinical systemic involvement. OBJECTIVES: A young woman presented with a painful swelling in her right hand. There were no signs of inflammation. Normal perfusion, mobility and sensibility were found. Magnetic resonance imaging (MRI) revealed a tumour infiltrating the muscles and flexor tendons of the third digit around the metacarpal bone and with pathological signal enhancement after administration of contrast medium. RESULTS: Intraoperatively, nodular masses and fat tissue were seen. Histological examination after radical tumour resection showed sarcoidal granulomas. Postoperative staging diagnostics with computed tomography (CT) demonstrated multiple thoracic lymph node swellings in the mediastinum and bilateral hill. Follow-up after one year we saw normal scars in the palmar hand. There was no sign of local recurrence. The pulmological care is still going on. CONCLUSIONS: Sarcoidosis is a rare, often asymptomatic disease. Patients present with dyspnoe and cough caused by the inflammation of the lung. The first clinical manifestation of sarcoidosis as a tumor in the palmar hand is unusual. Extrapulmonary systemic or progressive sarcoidosis is regarded as an indication for therapy with glucocorticosteroids. This case demonstrates that surgical excision enabled complete local cure without necessity of systemic and/or local treatment with steroids. |
| | |
Authors:
|
S Altmann; J Schreiber; H-G Damert; U Mirastschijski; W Schneider |
Related Documents
:
|
11580784 - Hypoxic brain damage after intramuscular self-injection of diclofenac for acute back pain. 11295354 - Assessment of scanner performance and normalization of estimated relaxation rate values. 8730194 - Brain death: mr and mr angiography. 19516904 - First reported case of cryptococcus gattii in the southeastern usa: implications for tr... 15615994 - Contrast-enhanced volumetric interpolated breath-hold examination compared with spin-ec... 2006004 - Celiac disease, brain atrophy, and dementia. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG / World Association of Sarcoidosis and Other Granulomatous Disorders Volume: 28 ISSN: 1124-0490 ISO Abbreviation: Sarcoidosis Vasc Diffuse Lung Dis Publication Date: 2011 Jul |
Date Detail:
|
Created Date: 2011-07-29 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9610928 Medline TA: Sarcoidosis Vasc Diffuse Lung Dis Country: Italy |
Other Details:
|
Languages: eng Pagination: 72-4 Citation Subset: IM |
Affiliation:
|
Department of Plastic, Aesthetic and Handsurgery, Otto-von-Guericke-University Magdeburg, Germany. silke.altmann@med.ovgu.de |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Type D or 'distressed' personality in sarcoidosis and idiopathic pulmonary fibrosis.
Next Document: Rapid improvement of osseous sarcoidosis after the treatment of pulmonary aspergillosis by itraconaz...