Document Detail

The involvement of medullary reticular formation in the hypotensive effect of extracts from seeds of Cassia tora.
MedLine Citation:
PMID:  998558     Owner:  NLM     Status:  MEDLINE    
In pentobarbital anesthetized rats, the medial portion of the medullary reticular formation has been identified to be directly involved in the hypotensive effect of extracts from the seeds of Cassia tora. This conclusion was drawn from the observed decrease in arterial blood pressure following local injection of extracts of this herb into this reticular site and from its inability to promote hypotension when the same reticular site has been electrolytically lesioned. The role of the medullary reticular formation in the Cassia tora-induced hypotension was suggested to be one which modulates the basic cardiovascular reflexes, favoring a decrease in vasomotor tone.
S H Chan; A Koo; K M Li
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The American journal of Chinese medicine     Volume:  4     ISSN:  0090-2942     ISO Abbreviation:  Am J Chin Med (Gard City N Y)     Publication Date:    1976 WINTER
Date Detail:
Created Date:  1977-01-29     Completed Date:  1977-01-29     Revised Date:  2005-06-14    
Medline Journal Info:
Nlm Unique ID:  0354717     Medline TA:  Am J Chin Med (Gard City N Y)     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  383-89     Citation Subset:  IM    
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MeSH Terms
Antihypertensive Agents / pharmacology*
Medulla Oblongata / drug effects*
Plant Extracts / pharmacology*
Plants, Medicinal*
Reticular Formation / drug effects*,  physiology
Reg. No./Substance:
0/Antihypertensive Agents; 0/Plant Extracts

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