Document Detail

An investigation of the relationship between cesarean section birth and respiratory distress syndrome of the newborn.
MedLine Citation:
PMID:  4014157     Owner:  NLM     Status:  MEDLINE    
To clarify the nature of the association between respiratory distress syndrome and Cesarean section birth, a study was conducted which compared 273 premature (36 weeks or less) Cesarean-delivered infants with 341 premature vaginally delivered infants who were born at the University of Washington Hospital from January 1, 1977 through March 31, 1980. The gestational age-adjusted probability of respiratory distress syndrome was higher among the Cesarean cohort compared with the vaginal cohort (38.2% vs. 27.6%, odds ratio = 1.63, 95% confidence interval = 1.11-2.39). Three alternative explanations for the association of Cesarean section with respiratory distress syndrome other than causation were tested, and each was rejected. The association was not explained by 1) improper timing of elective Cesarean deliveries; 2) misclassification of cases of mild, transient respiratory distress (which may be more common after Cesarean birth) as respiratory distress syndrome; or 3) the differences in the occurrence of pregnancy complications preceding Cesarean births compared with vaginal births. Lack of labor appears to account for part of the increased risk of respiratory distress syndrome among infants delivered by Cesarean section. The gestational age-adjusted probabilities of respiratory distress syndrome were 47.0% for Cesarean birth without labor, 35.4% for Cesarean birth preceded by labor, and 27.6% for vaginal birth.
E White; K K Shy; J R Daling
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  American journal of epidemiology     Volume:  121     ISSN:  0002-9262     ISO Abbreviation:  Am. J. Epidemiol.     Publication Date:  1985 May 
Date Detail:
Created Date:  1985-08-12     Completed Date:  1985-08-12     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  7910653     Medline TA:  Am J Epidemiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  651-63     Citation Subset:  IM    
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MeSH Terms
Birth Weight
Cesarean Section / adverse effects*
Gestational Age
Infant, Newborn
Labor, Obstetric*
Medical Records
Pregnancy Complications
Respiratory Distress Syndrome, Newborn / diagnosis,  etiology*
Grant Support
1 A03 00618//PHS HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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