Document Detail


An investigation of orotic acid levels in the breastmilk of smoking and non-smoking mothers.
MedLine Citation:
PMID:  12373615     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
AIM: In this study; orotic acid levels in the milk of smoking and non-smoking mothers were investigated by high-performance liquid chromatography (HPLC). RESULTS: It was found that the amount of orotic acid in the milk of smoking mothers (3.92+/-0.20 micro g/ml) was higher than that of non-smoking mothers (1.66+/-0.15 micro g/ml). Orotic acids levels in the milk of smoking mothers in comparison with non-smokers were found to be statistically significant (P<0.005). CONCLUSION: Smoking may have increased the orotic acid levels by affecting pyrimidine biosynthesis pathway.
Authors:
F Karatas
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  European journal of clinical nutrition     Volume:  56     ISSN:  0954-3007     ISO Abbreviation:  Eur J Clin Nutr     Publication Date:  2002 Oct 
Date Detail:
Created Date:  2002-10-09     Completed Date:  2002-12-30     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8804070     Medline TA:  Eur J Clin Nutr     Country:  England    
Other Details:
Languages:  eng     Pagination:  958-60     Citation Subset:  IM    
Affiliation:
Department of Chemistry, Firat University, Elazig 23119, Turkey. fkaratas1@hotmail.com
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MeSH Terms
Descriptor/Qualifier:
Adult
Chromatography, High Pressure Liquid / methods
Female
Humans
Infant, Newborn
Milk, Human / chemistry*
Orotic Acid / analysis*
Pyrimidines / biosynthesis
Smoking*
Uridine Monophosphate / metabolism
Chemical
Reg. No./Substance:
0/Pyrimidines; 289-95-2/pyrimidine; 58-97-9/Uridine Monophosphate; 65-86-1/Orotic Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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