Document Detail

An investigation, in vitro, of the actions of three Western Australian snakes on the blood coagulation of the dog, cat, horse and wallaby.
MedLine Citation:
PMID:  4062725     Owner:  NLM     Status:  MEDLINE    
Venoms of the tiger snake and brown snake were procoagulant, in vitro, when tested with cat, dog, horse and wallaby plasma. In the absence of calcium and phospholipid the coagulant activity of tiger snake venom was minimal. In contrast, brown snake venom alone had marked procoagulant activity. This activity, however, was enhanced by the presence of calcium and phospholipid. Death adder venom exerted an anticoagulant effect. Apparent species' differences in susceptibility to the coagulant venoms were noted. However, the probable explanation of these differences was attributed to variation in the control values of the special studies rather than to a difference in the postulated actions of the venoms on prothrombin. A possible role for clotting studies in suspected snake bite in veterinary practice is suggested.
A M Crawford; J N Mills
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Publication Detail:
Type:  In Vitro; Journal Article    
Journal Detail:
Title:  Australian veterinary journal     Volume:  62     ISSN:  0005-0423     ISO Abbreviation:  Aust. Vet. J.     Publication Date:  1985 Jun 
Date Detail:
Created Date:  1985-12-20     Completed Date:  1985-12-20     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370616     Medline TA:  Aust Vet J     Country:  AUSTRALIA    
Other Details:
Languages:  eng     Pagination:  185-6     Citation Subset:  IM    
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MeSH Terms
Blood Coagulation / drug effects*
Cats / blood*
Dogs / blood*
Elapid Venoms / pharmacology*
Horses / blood*
Macropodidae / blood*
Marsupialia / blood*
Reg. No./Substance:
0/Elapid Venoms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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