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The investigation of effects of fluorosis on thyroid volume in school-age children.
MedLine Citation:
PMID:  23348169     Owner:  NLM     Status:  Publisher    
Aim To compare the urine iodine, luoride, and to measure thyroid volumes in 10-15-year-old children using ultrasonography, a gold standard in evaluating thyroid volume. Methods A total of 261 children were enrolled into the study group from the 4-8th grades of 3 different primary schools, which were in the zone with high luoride levels. The control group was formed by enrolling 298 children from the 4-8th grades of only one primary school. Age, gender, height, and weight values were recorded for the children. The urine iodine, luoride, and thyroid volumes were measured with ultrasonography in 10-15-year-old children with luorosis and controls and compared between two groups. Results The mean urine luoride level was 0.48±0.24 mg/L in the study group and 0.22±0.17 mg/L in the control group (p less 0.001). The mean urine iodine level did not differ between two groups. The mean total thyroid volume was 8.60±3.11 mL and 8.73± 2.75 mL in the study and control group, respectively. The groups were also compared according to the echobody index, and the score was 6.94±2.14 ml/m² in the study group and 6.48±1.53 ml/m² in the control group (p=0.003). Mean thyroid volumes did not differ between two groups. However, the echobody index in the study group was higher than in the control group. Conclusion A relation between luoride concentration and thyroid gland with ultrasonographic examination was irstly evaluated, and it was concluded that luoride affected thyroid gland although it was weakly signiicant. After puberty, echobody index in subjects with luorosis was markedly high. Based on our results, we thought that luorosis increases thyroid volume in children with luorosis after puberty.
Ali Kutlucan; Banu Kale Koroglu; Mehmet Numan Tamer; Yusuf Aydin; Davut Baltaci; Mehmet Akdogan; Mustafa Ozturk; Huseyin Vural; Fatih Ermis
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Publication Detail:
Journal Detail:
Title:  Medicinski glasnik : official publication of the Medical Association of Zenica-Doboj Canton, Bosnia and Herzegovina     Volume:  10     ISSN:  1840-0132     ISO Abbreviation:  Med Glas Ljek komore Zenicko-doboj kantona     Publication Date:  2013 Feb 
Date Detail:
Created Date:  2013-1-25     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101250177     Medline TA:  Med Glas Ljek komore Zenicko-doboj kantona     Country:  -    
Other Details:
Languages:  ENG     Pagination:  93-98     Citation Subset:  -    
1Department of Internal Medicine, School of Medicine, Duzce University, Duzce, 2Department of Internal Medicine, Division of Endocri- nology, School of Medicine, Suleyman Demirel University, Isparta, 3Department of Family Medicine, School of Medicine, Duzce Univer- sity, Duzce, 4Department of Internal Medicine, Department of Biochemistry, School of Medicine, Suleyman Demirel University, Isparta, 5Department of Public Health, School of Medicine, Suleyman Demirel University, Isparta, 6Department of Gastroenterology, Isparta State Hospital, Isparta; Turkey.
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