Document Detail

Is intravenous contrast necessary for detection of clinically significant extracolonic findings in patients undergoing CT colonography?
MedLine Citation:
PMID:  24625066     Owner:  NLM     Status:  In-Data-Review    
Objective: To determine whether intravenous contrast (IVC) is necessary for detection of extracolonic findings (ECFs) in patients undergoing CT colonography (CTC). Methods: We performed a retrospective review of CT findings in 179 cases of CTC studies performed over 18 months where both pre-contrast (NECT) and post-contrast (CECT) scans were performed in the prone and supine positions, respectively, in the same patients. All ECFs were recorded on a per patient basis and graded according to the colonography reporting and data system classification. Results: There was no significant change in E grade for the cohort (p = 0.171) between the NECT and CECT scans. On the CECT scans, additional findings were detected in 49.1% of patients. Overall, there were 27/179 (15.1%) patients graded E3 and 18/179 (10.1%) patients graded E4 on the CECT study. Compared with the NECT study, there was a decrease of 12.9% of patients graded E3 and no change in the number of patients graded E4. Conclusion: With IVC administration, additional ECFs are detected in nearly half of all patients. However, there was no increase in the number of patients with clinically significant lesions. The risk-benefit ratio of routine IVC administration for CTC in symptomatic patients thus requires further evaluation. Advances in knowledge: This study reviews the utility of IVC in CTC and is thus relevant to current clinical practice at many institutions.
T Y Yau; Laa Alkandari; B Haaland; W Low; C H Tan
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Publication Detail:
Type:  Journal Article     Date:  2014-02-17
Journal Detail:
Title:  The British journal of radiology     Volume:  87     ISSN:  1748-880X     ISO Abbreviation:  Br J Radiol     Publication Date:  2014 Apr 
Date Detail:
Created Date:  2014-03-21     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0373125     Medline TA:  Br J Radiol     Country:  England    
Other Details:
Languages:  eng     Pagination:  20130667     Citation Subset:  AIM; IM    
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