| The interstitial cells of Cajal of the equine gastrointestinal tract: what we know so far. | |
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MedLine Citation:
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PMID: 20525058 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Gastrointestinal motility disorders are a serious problem in both veterinary and human medicine and may represent a dysfunction of the neural, muscular or pacemaker components (interstitial cells of Cajal) of bowel control. The interstitial cells of Cajal are considered to be the pacemakers and mediators of certain forms of neurotransmission in the gastrointestinal tract. These cells have been implicated, either primarily or secondarily, in the pathogenesis of gastrointestinal disease processes in which there is a prominent element of disturbance to intestinal motility. In the horse, their involvement has been implicated in large intestinal obstructive colic and grass sickness (equine dysautonomia). This review highlights the properties of the interstitial cells of Cajal and the role these cells play in orchestrating gastrointestinal motility patterns. In addition, it examines their role in intestinal motility disorders and summarises our current understanding of their importance in the equine gastrointestinal tract. |
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Authors:
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C Fintl; N P H Hudson |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Equine veterinary journal Volume: 42 ISSN: 0425-1644 ISO Abbreviation: Equine Vet. J. Publication Date: 2010 May |
Date Detail:
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Created Date: 2010-06-07 Completed Date: 2010-07-13 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0173320 Medline TA: Equine Vet J Country: England |
Other Details:
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Languages: eng Pagination: 372-7 Citation Subset: IM |
Affiliation:
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Norwegian School of Veterinary Science, Department of Companion Animal Clinical Sciences, PO Box 8146 Dep., 0033 Oslo, Norway. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Gastrointestinal Tract / cytology* Horses / anatomy & histology* Interstitial Cells of Cajal / cytology*, physiology* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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