| On the interpretation and use of <|E|2>(d*) profiles. | |
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MedLine Citation:
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PMID: 14747698 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Profiles of squared normalized structure factors, <|E|(2)>(d*), have been computed for a large number of proteins and nucleic acids. These are interpreted in terms of their underlying structural features. It is also shown that the 'solvent dip' at around 6.3 A resolution is to a large extent a protein secondary-structure effect that is enhanced by the water structure. A hierarchical classification of protein structures based on their <|E|(2)>(d*) profiles is briefly outlined, together with the use of <|E|(2)>(d*) profiles as an improvement over Wilson absolute scale estimation and as a novel solvent-modelling method. |
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Authors:
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Richard J Morris; Eric Blanc; Gérard Bricogne |
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Publication Detail:
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Type: Journal Article Date: 2004-01-23 |
Journal Detail:
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Title: Acta crystallographica. Section D, Biological crystallography Volume: 60 ISSN: 0907-4449 ISO Abbreviation: Acta Crystallogr. D Biol. Crystallogr. Publication Date: 2004 Feb |
Date Detail:
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Created Date: 2004-01-28 Completed Date: 2004-10-08 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9305878 Medline TA: Acta Crystallogr D Biol Crystallogr Country: Denmark |
Other Details:
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Languages: eng Pagination: 227-40 Citation Subset: IM |
Affiliation:
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Global Phasing Ltd, Sheraton House, Castle Park, Cambridge CB3 0AX, England. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Cluster Analysis Crystallography, X-Ray / methods Models, Statistical Nucleic Acids / chemistry* Protein Conformation Protein Structure, Secondary Proteins / chemistry* Solvents / chemistry Statistics as Topic / methods* Water / chemistry |
| Chemical | |
Reg. No./Substance:
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0/Nucleic Acids; 0/Proteins; 0/Solvents; 7732-18-5/Water |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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