| The interaction of antiarrhythmic drugs and the energy for cardioversion of chronic atrial fibrillation. | |
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MedLine Citation:
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PMID: 1715060 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Antiarrhythmic drugs may alter the energy for cardioversion of ventricular arrhythmias. This study compares the energy necessary for cardioverting chronic atrial fibrillation in 57 patients taking type Ia, Ic, or type III antiarrhythmic drugs. Patients taking Ia (n = 22) or III (n = 14) drugs had a median energy for cardioversion of 100 joules, while the patients taking Ic (n = 17) drugs had a median energy of 200 joules (P = 0.03). There were no differences in the frequency of unsuccessful cardioversion. There were no serious adverse events in any of the three groups, although three patients in the Ic group had greater than 3 second pauses after the shock. The data suggest that the use of Ic antiarrhythmic drugs results in a higher energy for cardioversion of atrial fibrillation. However with higher energies, conversion is as successful as for type Ia and type III. |
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Authors:
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T Guarnieri; G Tomaselli; L S Griffith; J Brinker |
Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Pacing and clinical electrophysiology : PACE Volume: 14 ISSN: 0147-8389 ISO Abbreviation: Pacing Clin Electrophysiol Publication Date: 1991 Jun |
Date Detail:
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Created Date: 1991-09-25 Completed Date: 1991-09-25 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7803944 Medline TA: Pacing Clin Electrophysiol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 1007-12 Citation Subset: IM |
Affiliation:
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Johns Hopkins University School of Medicine, Baltimore, Maryland. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Amiodarone
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therapeutic use Anti-Arrhythmia Agents / classification, therapeutic use* Atrial Fibrillation / drug therapy, therapy* Bradycardia / etiology Cerebrovascular Disorders / etiology Chronic Disease Electric Countershock* / methods Electrocardiography Energy Transfer Female Flecainide / therapeutic use Humans Male Middle Aged Quinidine / therapeutic use Stroke Volume / drug effects Time Factors |
| Chemical | |
Reg. No./Substance:
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0/Anti-Arrhythmia Agents; 1951-25-3/Amiodarone; 54143-55-4/Flecainide; 56-54-2/Quinidine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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