Document Detail

The interaction of MCI-154, a calcium sensitizer, and isoflurane on systemic and coronary hemodynamics in chronically instrumented dogs.
MedLine Citation:
PMID:  14693578     Owner:  NLM     Status:  MEDLINE    
IMPLICATIONS: MCI-154, a calcium sensitizer, restores the myocardial contractility depressed by isoflurane and enhances the coronary vasodilating effect of isoflurane in chronically instrumented dogs.
Shunji Takahashi; Sungsam Cho; Tetsuya Hara; Hiroyuki Ureshino; Shiro Tomiyasu; Koji Sumikawa
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Anesthesia and analgesia     Volume:  98     ISSN:  0003-2999     ISO Abbreviation:  Anesth. Analg.     Publication Date:  2004 Jan 
Date Detail:
Created Date:  2003-12-24     Completed Date:  2004-01-20     Revised Date:  2013-05-20    
Medline Journal Info:
Nlm Unique ID:  1310650     Medline TA:  Anesth Analg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  30-6, table of contents     Citation Subset:  AIM; IM    
Department of Anesthesiology, Nagasaki University School of Medicine, 1-7-1 Sakamoto, Nagasaki 852-8501, Japan.
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MeSH Terms
Anesthetics, Inhalation / pharmacology*
Autonomic Nervous System / drug effects
Blood Pressure / physiology
Calcium / physiology*
Cardiotonic Agents / pharmacology*
Coronary Circulation / drug effects*
Heart / innervation
Hemodynamics / drug effects*
Isoflurane / pharmacology*
Myocardial Contraction / drug effects
Oxygen Consumption / drug effects
Pyridazines / pharmacology*
Stroke Volume / physiology
Ventricular Function, Left / physiology
Reg. No./Substance:
0/Anesthetics, Inhalation; 0/Cardiotonic Agents; 0/Pyridazines; 26675-46-7/Isoflurane; 7440-70-2/Calcium; 98326-33-1/MCI 154

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