Document Detail


The inter- and intra-tribal distribution of red cell G6PD phenotypes in Sudan.
MedLine Citation:
PMID:  6840777     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
1,416 males and 564 female subjects from four Negroid and five Arab tribes and a group of mixed tribes of the Sudan were investigated for the phenotypic distribution of red cell glucose-6-phosphate dehydrogenase by starch gel electrophoresis. In general, the tribes of Negroid origin had higher frequency of GdA compared to the tribes of Arab ancestry. However, the Nilotes showed a lower frequency of GdA allele and the Mahass tribe claiming an Arab origin had a higher frequency of GdA. The immigrant groups from the neighbouring African countries also had a higher frequency of GdA. GdB (Khartoum) was present in low frequencies in both the Arab and Negroid tribes. A great deal of intratribal variation in the phenotypic distribution of G6PD was observed in the Nuba and Gáali tribes from different localities.
Authors:
N Saha; A P Samuel; A Omer; A V Hoffbrand
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Human heredity     Volume:  33     ISSN:  0001-5652     ISO Abbreviation:  Hum. Hered.     Publication Date:  1983  
Date Detail:
Created Date:  1983-06-23     Completed Date:  1983-06-23     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0200525     Medline TA:  Hum Hered     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  39-43     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
African Continental Ancestry Group
Alleles
Erythrocytes / enzymology*
Ethnic Groups
Female
Gene Frequency
Glucosephosphate Dehydrogenase / genetics*
Humans
Male
Phenotype
Sudan
Chemical
Reg. No./Substance:
EC 1.1.1.49/Glucosephosphate Dehydrogenase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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