Document Detail


The integrity of tubular cell function after preservation in Collins' or Sacks' solution.
MedLine Citation:
PMID:  1273913     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Collins' solution is an excellent medium for kidney preservation by simple cold storage before transplantation. Efforts by Sacks et al. to improve this technique by modifying the composition seemed promising. A comparison between ability of these two media to preserve the tubular cell was attempted. The viability of the tubular cells was evaluated by measuring the 125 I Hippuran uptake in cortex slices taken from kidneys preserved for 24 and 48 hr in the respective solutions. Kidneys exposed to as well as kidneys not exposed to warm ischaemia were used. Collins' solution was found to be superior in protecting the cell function. Nonetheless intracellular oedema during preservation was greater after preservation in this solution as compared with cells preserved in Sacks' solution.
Authors:
J I Dahlager; T Bilde
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Transplantation     Volume:  21     ISSN:  0041-1337     ISO Abbreviation:  Transplantation     Publication Date:  1976 May 
Date Detail:
Created Date:  1976-08-02     Completed Date:  1976-08-02     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0132144     Medline TA:  Transplantation     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  365-9     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Kidney Cortex / anatomy & histology
Kidney Tubules / cytology,  physiology*
Organ Preservation / methods*
Organ Size
Rabbits
Solutions
Tissue Preservation / methods*
Chemical
Reg. No./Substance:
0/Solutions

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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