| The injured lung: clinical issues and experimental models. | |
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MedLine Citation:
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PMID: 21149368 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Exposure of military and civilian populations to inhaled toxic chemicals can take place as a result of deliberate release (warfare, terrorism) or following accidental releases from industrial concerns or transported chemicals. Exposure to inhaled toxic chemicals can result in an acute lung injury, and in severe cases acute respiratory distress syndrome, for which there is currently no specific medical therapy, treatment remaining largely supportive. This treatment often requires intensive care facilities that may become overwhelmed in mass casualty events and may be of limited benefit in severe cases. There remains, therefore, a need for evidence-based treatment to inform both military and civilian medical response teams on the most appropriate treatment for chemically induced lung injury. This article reviews data used to derive potential clinical management strategies for chemically induced lung injury. |
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Authors:
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B J A Jugg; A J Smith; S J Rudall; P Rice |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Philosophical transactions of the Royal Society of London. Series B, Biological sciences Volume: 366 ISSN: 1471-2970 ISO Abbreviation: Philos. Trans. R. Soc. Lond., B, Biol. Sci. Publication Date: 2011 Jan |
Date Detail:
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Created Date: 2010-12-14 Completed Date: 2011-03-29 Revised Date: 2012-01-27 |
Medline Journal Info:
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Nlm Unique ID: 7503623 Medline TA: Philos Trans R Soc Lond B Biol Sci Country: England |
Other Details:
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Languages: eng Pagination: 306-9 Citation Subset: IM |
Affiliation:
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Biomedical Sciences Department, Dstl Porton Down, Salisbury SP4 OJQ, UK. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acute Lung Injury
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chemically induced,
physiopathology*,
therapy* Animals Disease Management* Disease Models, Animal Evidence-Based Practice / methods Hazardous Substances / toxicity* Humans Military Medicine / methods*, trends Military Personnel Sus scrofa War* |
| Chemical | |
Reg. No./Substance:
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0/Hazardous Substances |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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