Document Detail


The inhibitory effect of radix Salviae miltiorrhizae on hypoxic structural remodeling of intra-acinar pulmonary arteries.
MedLine Citation:
PMID:  7807599     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The inhibitory effect of Radix Salviae Miltiorrhizae (RSM) on hypoxic structural remodeling of intra-acinar pulmonary arteries (IAPA) was observed by light and electron microscopy and morphometry. It was found that RSM can not only dilate IAPA and relieve the hypoxic injuries to endothelia cells, but also inhibit the active muscularization of IAPA in the hypoxic animals, suggesting that RSM plays a very important role in inhibiting structural remodeling of IAPA and pulmonary hypertension.
Authors:
S C Xi; D Y Che; W R Zhang
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of Tongji Medical University = Tong ji yi ke da xue xue bao     Volume:  14     ISSN:  0257-716X     ISO Abbreviation:  J. Tongji Med. Univ.     Publication Date:  1994  
Date Detail:
Created Date:  1995-01-27     Completed Date:  1995-01-27     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  8605495     Medline TA:  J Tongji Med Univ     Country:  CHINA    
Other Details:
Languages:  eng     Pagination:  148-52     Citation Subset:  IM    
Affiliation:
Department of Pathology, Tongji Medical University, Wuhan.
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MeSH Terms
Descriptor/Qualifier:
Animals
Anoxia / drug therapy,  pathology*
Drugs, Chinese Herbal / pharmacology*
Endothelium, Vascular / pathology*
Muscle, Smooth, Vascular / pathology
Plant Extracts
Pulmonary Artery / drug effects*,  pathology
Rats
Rats, Sprague-Dawley
Salvia miltiorrhiza
Chemical
Reg. No./Substance:
0/Drugs, Chinese Herbal; 0/Plant Extracts

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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