| The influence of wavelength and probe configuration on findings of a skin vasoconstriction test when using laser Doppler perfusion devices. | |
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MedLine Citation:
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PMID: 16403539 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The aim of this study was to establish the degree to which a standardized test based on laser Doppler blood flow measurement is dependent on the particular equipment set-up being used. For this purpose, we examined finger skin blood flow with laser Doppler instruments in 20 healthy subjects. In laser Doppler perfusion monitoring (LDPM), we used a custom-made probe with two detecting fibers placed 0.25 and 1.2 mm from the illuminating fiber, respectively, and two laser Doppler perfusion imagers (LDPI) with a wavelength of 632.8 nm and 780 nm, respectively. Warming of the hand was achieved with a Peltier element, and reflex vasoconstriction was induced by immersing the other hand for 3 min into a water bath kept at 15 degrees C. As a measure for the change in skin blood flow, a vasoconstriction index (VAC: cooling/before cooling) was calculated and used for the comparison of the different devices. VAC values gathered around 0.6 for all devices. However, LDPI with a wavelength of 632.8 nm showed a slightly higher VAC index, and the difference was significant. We conclude that using a standardized test is the most appropriate for monitoring changes in blood flow rather than recording and comparing discrete values in intermittent recordings. Although a difference was noted when comparing the devices, different fiber separations and wavelengths seem then to be of little consequence. |
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Authors:
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Carolin Freccero; Per Wollmer; Göran Sundkvist; Henry Svensson |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2006-01-05 |
Journal Detail:
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Title: Microvascular research Volume: 71 ISSN: 0026-2862 ISO Abbreviation: Microvasc. Res. Publication Date: 2006 Jan |
Date Detail:
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Created Date: 2006-02-03 Completed Date: 2006-04-06 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0165035 Medline TA: Microvasc Res Country: United States |
Other Details:
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Languages: eng Pagination: 64-7 Citation Subset: IM |
Affiliation:
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Department of Plastic and Reconstructive Surgery, Malmö University Hospital, University of Lund, SE-20502 Malmö, Sweden. carolin.freccero@plastsurg.mas.lu.se |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Fingers / blood supply Humans Laser-Doppler Flowmetry / instrumentation, methods* Male Monitoring, Physiologic Perfusion Regional Blood Flow Skin / blood supply*, ultrasonography* Skin Temperature Skin Tests Time Factors Vasoconstriction / physiology* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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