Document Detail

The influence of volatile anesthetics on portwine stain.
MedLine Citation:
PMID:  8364948     Owner:  NLM     Status:  MEDLINE    
To examine the relationship between volatile inhalation anesthetics and the fading of portwine stain (PWS), the study retrospectively investigated the incidence of termination of pulsed dye laser treatment vis-à-vis PWS fade during use of a general inhalation anesthetic in 107 infants and children with facial PWS. The fading of PWS is disadvantageous to the pulsed dye laser treatment. All patients received pulsed dye laser treatment under general anesthesia using one of four kinds of volatile inhalation anesthetics (halothane, enflurane, isoflurane, and sevoflurane). Two hours before the induction of anesthesia, all patients were rectally irrigated. Treatment was discontinued in none of the 44 patients in the halothane group or the 7 patients in the enflurane group; in one of the 29 in the isoflurane group; and in 10 of the 27 patients in the sevoflurane group. The sevoflurane group showed a significantly (P < 0.01) higher incidence of PWS fading. Thus, when using a volatile inhalation anesthetic in combination with pulsed dye laser treatment for PWS, caution should be exercised if sevoflurane is selected, as PWS fading is harmful to the pulsed dye laser.
K Tanaka; M Nakamura; M Domen; M Arimitsu; T Izumi; T Okuda; K Suekane; T Tezuka
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical therapeutics     Volume:  15     ISSN:  0149-2918     ISO Abbreviation:  Clin Ther     Publication Date:    1993 May-Jun
Date Detail:
Created Date:  1993-10-04     Completed Date:  1993-10-04     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  7706726     Medline TA:  Clin Ther     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  567-9     Citation Subset:  IM    
Department of Anesthesiology, Kinki University School of Medicine, Osaka-Sayama, Japan.
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MeSH Terms
Anesthesia, General*
Anesthesia, Inhalation*
Anesthetics / adverse effects*
Child, Preschool
Ethers / adverse effects*
Laser Therapy*
Methyl Ethers*
Nevus / surgery*
Reg. No./Substance:
0/Anesthetics; 0/Ethers; 0/Methyl Ethers; 28523-86-6/sevoflurane

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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