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The influence of timing of polysomnography on diagnosis of obstructive sleep apnea in patients presenting with acute myocardial infarction and stable coronary artery disease.
MedLine Citation:
PMID:  23890600     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
BACKGROUND: We aimed to determine if timing of polysomnography (PSG) influences the diagnosis of obstructive sleep apnea (OSA) in acute myocardial infarction (AMI) or stable coronary artery disease (CAD).
METHODS: A total of 160 patients admitted with AMI or stable CAD were consecutively recruited for either in-hospital (n=80) or postdischarge (n=80) PSG.
RESULTS: The median time from admission to PSG for the in-hospital and postdischarge groups was 1day and 17days, respectively (P<.001). Overall, 59 patients (36.9%) were diagnosed with OSA (apnea-hypopnea index [AHI] ⩾15), and they were more likely to have diabetes mellitus (DM), hypertension, hyperlipidemia, chronic renal failure, and a greater body mass index (BMI) (P<.05 for all). The diagnosis of OSA was significantly higher (P=.037) in patients who had a PSG performed as an inpatient than those who had a PSG as an outpatient. There was a significant interaction between clinical presentation and the effect of PSG timing on the diagnosis of OSA (P=.003). For the patients presenting with AMI but not those with stable CAD, in-hospital PSG was an independent predictor of OSA (adjusted odds ratio, 3.84 [95% confidence interval, 1.42-10.41]; P=.008).
CONCLUSION: The timing of PSG influenced the diagnosis of OSA in patients who presented with AMI but not in those who presented with stable CAD.
Authors:
Ting-Ting Low; Wei-Zhen Hong; Bee-Choo Tai; Thet Hein; See-Meng Khoo; Adeline Y Tan; Mark Y Chan; Mark Richards; Chi-Hang Lee
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-7-24
Journal Detail:
Title:  Sleep medicine     Volume:  -     ISSN:  1878-5506     ISO Abbreviation:  Sleep Med.     Publication Date:  2013 Jul 
Date Detail:
Created Date:  2013-7-29     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100898759     Medline TA:  Sleep Med     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2013 Elsevier B.V. All rights reserved.
Affiliation:
Department of Cardiology, National University Heart Centre, Singapore.
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