Document Detail

The influence of syringomycin on ribonucleic acid synthesis.
MedLine Citation:
PMID:  5817186     Owner:  NLM     Status:  MEDLINE    
Syringomycin, a wide-spectrum antibiotic produced by strains of Pseudomonas syringae which cause bacterial canker of peach, was able to bind to salmon sperm and calf thymus deoxyribonucleic acid but not to calf thymus histone; it also inhibited ribonucleic acid polymerase activity. These abilities to bind to deoxyribonucleic acid and to inhibit ribonucleic acid polymerase were inactivated when the phytotoxic and antibiotic properties of syringomycin were inactivated.
D Penner; J E DeVay; P Backman
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Publication Detail:
Type:  In Vitro; Journal Article    
Journal Detail:
Title:  Plant physiology     Volume:  44     ISSN:  0032-0889     ISO Abbreviation:  Plant Physiol.     Publication Date:  1969 Jun 
Date Detail:
Created Date:  1969-10-15     Completed Date:  1969-10-15     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0401224     Medline TA:  Plant Physiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  806-8     Citation Subset:  IM    
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MeSH Terms
Anti-Bacterial Agents / pharmacology*
DNA / metabolism*
Protein Binding
RNA / biosynthesis*
RNA Nucleotidyltransferases / antagonists & inhibitors*
Thymus Gland
Reg. No./Substance:
0/Anti-Bacterial Agents; 63231-63-0/RNA; 9007-49-2/DNA; EC 2.7.7.-/RNA Nucleotidyltransferases

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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